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Article

<i>Gpnmb</i> is a melanoblast‐expressed, MITF‐dependent gene

1 Nov 2008

Abstract excerpt

Expression profile analysis clusters Gpnmb with known pigment genes, Tyrp1, Dct, and Si. During development, Gpnmb is expressed in a pattern similar to Mitf, Dct and Si with expression vastly reduced in Mitf mutant animals. Unlike Dct and Si, Gpnmb remains expressed in a discrete population of caudal melanoblasts in Sox10-deficient embryos. To understand the transcriptional regulation of Gpnmb we performed a...

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PMID: 18983539
DOI: 10.1111/j.1755-148x.2008.00518.x

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