Article
Association of caspases with an increased prostate cancer risk in north Indian population.
DNA and cell biology - 1 Jan 2012
Mittal Rama Devi, Mittal Tulika, Singh Abhinav K, Mandal Raju K
Abstract excerpt
Dysregulation of apoptosis plays a crucial role in carcinogenesis. Thus, genetic alterations within caspase genes would be expected to provoke a deficient apoptotic signaling thereby facilitating the development of prostate cancer (PCa). In the present study we investigated whether three different polymorphisms in the caspase-5 and -3 genes are differentially expressed in PCa. In a hospital-based case control...
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