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Article

A minor arginine tRNA mutant limits translation preferentially of a protein dependent on the cognate codon.

Journal of bacteriology - 1 May 1990

Chen K S, Peters T C, Walker J R

Abstract excerpt

The Escherichia coli argU gene encodes a rare arginine tRNA (anticodon UCU) that translates the similarly rare AGA codon. The argU10(Ts) mutation is a transition that changes the first nucleotide of the mature tRNA from G to A, presumably destabilizing the acceptor stem. This mutation, when present in haploid condition in the chromosome, reduces the growth rate at 30 degrees C and results in cessation of growth...

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Identifiers

PMID: 2139647
DOI: 10.1128/jb.172.5.2504-2510.1990
PMCID: PMC208890

Genes

AGA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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