Article
The tRNA function of SsrA contributes to controlling repression of bacteriophage Mu prophage.
Proceedings of the National Academy of Sciences of the United States of America - 28 Aug 2001
Ranquet C, Geiselmann J, Toussaint A
Abstract excerpt
The small regulatory RNA SsrA has both tRNA and mRNA activities. It charges alanine and interacts with stalled ribosomes, allowing for translation to resume on the SsrA mRNA moiety. Hence, unfinished peptides carry a short amino acid tag, which serves as a signal for degradation by energy-dependent proteases. In SsrA-defective Escherichia coli strains, thermoinducible mutants of the transposable bacteriophage Mu...
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