Article
The evolutionarily conserved eukaryotic arginine attenuator peptide regulates the movement of ribosomes that have translated it.
Molecular and cellular biology - 1 Dec 1998
Wang Z, Fang P, Sachs M S
Abstract excerpt
Translation of the upstream open reading frame (uORF) in the 5' leader segment of the Neurospora crassa arg-2 mRNA causes reduced initiation at a downstream start codon when arginine is plentiful. Previous examination of this translational attenuation mechanism using a primer-extension inhibition...
Topics
- Amino Acid Sequence
- Arginine
- Base Sequence
- Carbon-Nitrogen Ligases with Glutamine as Amide-N-Donor
- Codon
- Conserved Sequence
- DNA-Directed RNA Polymerases
- Fungal Proteins
- Genes, Reporter
- Molecular Sequence Data
- Mutation
- Neurospora crassa
- Open Reading Frames
- Peptide Chain Elongation, Translational
- Peptide Fragments
- Peptides
- Protein Biosynthesis
- Protein Sorting Signals