Article
Probable role of beta2-adrenergic receptor gene haplotype in high-altitude pulmonary oedema.
Respirology (Carlton, Vic.) - 1 May 2010
Stobdan Tsering, Kumar Ram, Mohammad Ghulam, Thinlas Tashi, Norboo Tsering, Iqbal Mohammad, Pasha M A Qadar
Abstract excerpt
BACKGROUND AND OBJECTIVE: The role of beta2-adrenergic receptor (ADRB2) in pulmonary oxygenation has been ascertained during altitude acclimatization, physical performance and lung fluid clearance, but little is known about its association with high-altitude pulmonary oedema (HAPE), a non-cardiogenic pulmonary oedema. METHODS: In a case-control study, 110 unrelated HAPE patients (HAPE-p) and 143 unrelated...
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