Article
Polymorphisms of angiotensin converting enzyme and nitric oxide synthase 3 genes as risk factors of high-altitude pulmonary edema: a case-control study and meta-analysis.
The Tohoku journal of experimental medicine - 1 Apr 2013
Wang Qing-Qing, Yu Lei, Huang Guo-Rong, Zhang Lu, Liu Ya-Qiong, Wang Tai-Wu, Lin Hui, Ren Qian, Liu Ping, Huang Lan, Qin Jun, Wu Guo-Ming, Li Qian-Ning, Li Ya-Fei, Xiong Hong-Yan
Abstract excerpt
High-altitude pulmonary edema (HAPE) is a non-cardiogenic type of pulmonary edema developing altitudes > 2,500 m. Angiotensin converting enzyme (ACE) and nitric oxide synthase 3 (NOS3) play important roles in regulating pulmonary vascular tone. To assess associations between genetic variants in the ACE and NOS3 genes and HAPE risk, 27 HAPE patients and 108 matched controls were genotyped and analyzed. The...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.