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Article

Deficient CEBPA DNA binding function in normal karyotype AML patients is associated with favorable prognosis.

Blood - 5 May 2011

Fos José, Pabst Thomas, Petkovic Vibor, Ratschiller Daniel, Mueller Beatrice U

Abstract excerpt

CCAAT/enhancer binding protein-α (CEBPA) mutations in acute myeloid leukemia (AML) patients with a normal karyotype (NK) confer favorable prognosis, whereas NK-AML patients per se are of intermediate risk. This suggests that blocked CEBPA function characterizes NK-AML with favorable outcome. We determined the prognostic significance of CEBPA DNA binding function by enzyme-linked immunosorbent assay in 105 NK-AML...

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Share to CCAAT-Enhancer-Binding Proteins
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21389317
DOI: 10.1182/blood-2010-11-320747

Genes

FLT3
NPM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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