Article
Risk assessment in patients with acute myeloid leukemia and a normal karyotype.
Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Feb 2005
Bienz Marianne, Ludwig Madleina, Leibundgut Elisabeth Oppliger, Mueller Beatrice U, Ratschiller Daniel, Solenthaler Max, Fey Martin F, Pabst Thomas
Abstract excerpt
PURPOSE: The recognition of a number of leukemia-specific cytogenetic abnormalities and their role as independent prognostic factors have provided considerable insights into leukemia pathogenesis and have paved the way to adopt risk-adapted treatment. However, approximately 50% of newly diagnosed acute myeloid leukemia (AML) have a normal karyotype. There has therefore been much interest in identifying molecular...
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