The rs8099917 polymorphism, when determined by a suitable genotyping method, is a better predictor for response to pegylated alpha interferon/ribavirin therapy in Japanese patients than other single nucleotide polymorphisms associated with interleukin-28B.

doi:10.1128/JCM.02139-10

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Article

The rs8099917 polymorphism, when determined by a suitable genotyping method, is a better predictor for response to pegylated alpha interferon/ribavirin therapy in Japanese patients than other single nucleotide polymorphisms associated with interleukin-28B.

Journal of clinical microbiology - 1 May 2011

Ito Kiyoaki, Higami Katsuya, Masaki Naohiko, Sugiyama Masaya, Mukaide Motokazu, Saito Hiroaki, Aoki Yoshihiko, Sato Yo, Imamura Masatoshi, Murata Kazumoto, Nomura Hideyuki, Hige Shuhei, Adachi Hiroshi, Hino Keisuke, Yatsuhashi Hiroshi, Orito Etsuro, Kani Satomi, Tanaka Yasuhito, Mizokami Masashi

Abstract excerpt

We focused on determining the most accurate and convenient genotyping methods and most appropriate single nucleotide polymorphism (SNP) among four such polymorphisms associated with interleukin-28B (IL-28B) in order to design tailor-made therapy for patients with chronic hepatitis C virus (HCV) patients. First, five different methods (direct sequencing, high-resolution melting analysis [HRM], hybridization probe...

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Identifiers

PMID: 21389156
DOI: 10.1128/JCM.02139-10
PMCID: PMC3122695

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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