Article
Prediction of response to peginterferon-alfa-2b plus ribavirin therapy in Japanese patients infected with hepatitis C virus genotype 1b.
Journal of medical virology - 1 Jun 2011
Hashimoto Yoshimasa, Ochi Hidenori, Abe Hiromi, Hayashida Yasufumi, Tsuge Masataka, Mitsui Fukiko, Hiraga Nobuhiko, Imamura Michio, Takahashi Shoichi, Nelson Hayes C, Ohishi Waka, Kubo Michaki, Tsunoda Tatsuhiko, Kamatani Naoyuki, Nakamura Yusuke, Chayama Kazuaki
Abstract excerpt
Variation at the IL-28B locus was recently reported to be a significant predictive factor of viral response to pegylated-interferon plus ribavirin combination therapy against chronic hepatitis C. Predictive factors for the effect of therapy, including IL-28B polymorphism rs8099917 and viral and clinical factors were investigated. A total of 288 patients were enrolled who were chronically infected with hepatitis C...
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