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Article

Fat maintenance is a predictor of the murine lifespan response to dietary restriction.

Aging cell - 1 Aug 2011

Liao Chen-Yu, Rikke Brad A, Johnson Thomas E, Gelfond Jonathan A L, Diaz Vivian, Nelson James F

Abstract excerpt

Dietary restriction (DR), one of the most robust life-extending manipulations, is usually associated with reduced adiposity. This reduction is hypothesized to be important in the life-extending effect of DR, because excess adiposity is associated with metabolic and age-related disease. Previously, we described remarkable variation in the lifespan response of 41 recombinant inbred strains of mice to DR, ranging...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21388497
DOI: 10.1111/j.1474-9726.2011.00702.x
PMCID: PMC3685291

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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