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Article

Reevaluation of the effect of dietary restriction on different recombinant inbred lines of male and female mice.

Aging cell - 1 Nov 2021

Unnikrishnan Archana, Matyi Stephanie, Garrett Karla, Ranjo-Bishop Michelle, Allison David B, Ejima Keisuke, Chen Xiwei, Dickinson Stephanie, Richardson Arlan

Abstract excerpt

Dietary restriction (DR) was reported to either have no effect or reduce the lifespan of the majority of the 41-recombinant inbred (RI) lines studied by Liao et al. (Aging Cell, 2010, 9, 92). In an appropriately power longevity study (n > 30 mice/group), we measured the lifespan of the four RI lines (115-RI, 97-RI, 98-RI, and 107-RI) that were reported to have the greatest decrease in lifespan when fed 40% DR. DR...

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Identifiers

PMID: 34713968
DOI: 10.1111/acel.13500
PMCID: PMC8590105

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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