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Article

Genetic variation in responses to dietary restriction--an unbiased tool for hypothesis testing.

Experimental gerontology - 1 Oct 2013

Liao Chen-Yu, Johnson Thomas E, Nelson James F

Abstract excerpt

Dietary restriction (DR) extends lifespan in a wide range of animal models. A major obstacle to understanding how DR modulates lifespan and aging-related dysfunction is the multiplicity of physiological and molecular changes associated with DR. Unraveling their importance to the longevity effect of DR remains a major challenge. In this perspective, we review the marked genetic variation in the response to DR of...

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Identifiers

PMID: 23562825
DOI: 10.1016/j.exger.2013.03.010
PMCID: PMC3759609

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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