Article
Gene-by-environmental modulation of longevity and weight gain in the murine BXD family
2019-09-19
Abstract excerpt
<h4>Summary</h4> Diet and environment profoundly modulate lifespan. We measured longevity as a function of diet and weight gain across a genetically diverse family of mice. We followed 1348 females from two parental strains—C57BL/6J and DBA/2J—and 146 cohorts of BXD isogenic progeny strains ( n = 73) across their lifespan on a low fat chow diet (CD, 18% calories from fat) and on a high fat diet (HFD, 60% calorie...
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Identifiers and source
- Literature Corpus work
- 79ccbadf-95e9-5aa8-b09a-72ed562a00ef
- DOI
- 10.1101/776559