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Article

Genetic variation in the transforming growth factor-β signaling pathway and survival after diagnosis with colon and rectal cancer.

Cancer - 15 Sept 2011

Slattery Martha L, Lundgreen Abbie, Herrick Jennifer S, Wolff Roger K, Caan Bette J

Abstract excerpt

BACKGROUND: The transforming growth factor-β (TGF-β) signaling pathway is involved in many aspects of tumorigenesis, including angiogenesis and metastasis. The authors evaluated this pathway in association with survival after a diagnosis of colon or rectal cancer. METHODS: The study included 1553 patients with colon cancer and 754 patients with rectal cancer who had incident first primary disease and were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21365634
DOI: 10.1002/cncr.26018
PMCID: PMC3476941

Genes

BMP1
BMP2
BMP4
BMPR2
GDF10
MAPK1
RUNX1
RUNX2
RUNX3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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