Article
Genotypic and phenotypic modifications of Neisseria meningitidis after an accidental human passage.
PloS one - 28 Feb 2011
Omer Hélène, Rose Graham, Jolley Keith A, Frapy Eric, Zahar Jean-Ralph, Maiden Martin C J, Bentley Stephen D, Tinsley Colin R, Nassif Xavier, Bille Emmanuelle
Abstract excerpt
A scientist in our laboratory was accidentally infected while working with Z5463, a Neisseria meningitidis serogroup A strain. She developed severe symptoms (fever, meningism, purpuric lesions) that fortunately evolved with antibiotic treatment to complete recovery. Pulse-field gel electrophoresis confirmed that the isolate obtained from the blood culture (Z5463BC) was identical to Z5463, more precisely to a...
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