Article
Meningococcal genetic variation mechanisms viewed through comparative analysis of serogroup C strain FAM18.
PLoS genetics - 16 Feb 2007
Bentley Stephen D, Vernikos George S, Snyder Lori A S, Churcher Carol, Arrowsmith Claire, Chillingworth Tracey, Cronin Ann, Davis Paul H, Holroyd Nancy E, Jagels Kay, Maddison Mark, Moule Sharon, Rabbinowitsch Ester, Sharp Sarah, Unwin Louise, Whitehead Sally, Quail Michael A, Achtman Mark, Barrell Bart, Saunders Nigel J, Parkhill Julian
Abstract excerpt
The bacterium Neisseria meningitidis is commonly found harmlessly colonising the mucosal surfaces of the human nasopharynx. Occasionally strains can invade host tissues causing septicaemia and meningitis, making the bacterium a major cause of morbidity and mortality in both the developed and developing world. The species is known to be diverse in many ways, as a product of its natural transformability and of a...
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