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Article

Likelihood ratio testing for admixture models with application to genetic linkage analysis.

Biometrics - 1 Dec 2011

Di Chong-Zhi, Liang Kung-Yee

Abstract excerpt

We consider likelihood ratio tests (LRT) and their modifications for homogeneity in admixture models. The admixture model is a two-component mixture model, where one component is indexed by an unknown parameter while the parameter value for the other component is known. This model is widely used in genetic linkage analysis under heterogeneity in which the kernel distribution is binomial. For such models, it is...

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Identifiers

PMID: 21385166
DOI: 10.1111/j.1541-0420.2011.01574.x
PMCID: PMC3120934

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