Article
Protection by inhibitors of multidrug resistance against mitochondrial mutagenesis in Saccharomyces cerevisiae.
European journal of cancer (Oxford, England : 1990) - 1 Jan 1990
Baguley B C, Turner P M, Ferguson L R
Abstract excerpt
A number of inhibitors thought to act on the drug efflux mechanism of multidrug-resistant cells have been tested for their ability to inhibit the induction of respiration-deficient (petite) colonies of the yeast Saccharomyces cerevisiae by mitochondrial mutagens. The mutagens tested were 3,6-diam...
Topics
- Aminoacridines
- Chloroquine
- Drug Resistance
- Mitochondria
- Mutagens
- Mutation
- Polysorbates
- Saccharomyces cerevisiae
- Verapamil
