Article
Induction of respiration-deficient mutants in Saccharomyces cerevisiae by chelerythrine.
FEMS microbiology letters - 1 Jul 1994
Krivjanský V, Obernauerová M, Ulrichová J, Simánek V, Subík J
Abstract excerpt
Chelerythrine and sanguinarine, two structurally related benzo/c/phenanthridine alkaloids, prevented growth of yeast cells in medium containing either glucose or non-fermentable carbon sources. At concentrations permitting growth of the yeast Saccharomyces cerevisiae, chelerythrine, but not sanquinarine, induced cytoplasmic respiration-deficient mutants. The petite clones that were analysed exhibited...
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