Article
Impact of mitochondrial function on yeast susceptibility to antifungal compounds.
Folia microbiologica - 1 Jan 2007
Sarinová M, Tichá E, Obernauerová M, Gbelská Y
Abstract excerpt
Saccharomyces cerevisiae pell and crd1 mutants deficient in the biosynthesis of mitochondrial phosphatidylglycerol (PG) and cardiolipin (CL) as well as Kluyveromyces lactis mutants impaired in the respiratory chain function (RCF) containing dysfunctional mitochondria show altered sensitivity to metabolic inhibitors. The S. cerevisiae pell mutant displayed increased sensitivity to cycloheximide, chloramphenicol,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
