Article
The Drosophila zinc finger protein trade embargo is required for double strand break formation in meiosis.
PLoS genetics - 1 Feb 2011
Lake Cathleen M, Nielsen Rachel J, Hawley R Scott
Abstract excerpt
Homologous recombination in meiosis is initiated by the programmed induction of double strand breaks (DSBs). Although the Drosophila Spo11 ortholog Mei-W68 is required for the induction of DSBs during meiotic prophase, only one other protein (Mei-P22) has been shown to be required for Mei-W68 to exert this function. We show here that the chromatin-associated protein Trade Embargo (Trem), a C2H2 zinc finger...
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