Article
mei-W68 in Drosophila melanogaster encodes a Spo11 homolog: evidence that the mechanism for initiating meiotic recombination is conserved.
Genes & development - 15 Sept 1998
McKim K S, Hayashi-Hagihara A
Abstract excerpt
Meiotic recombination requires the action of several gene products in both Saccharomyces cerevisiae and Drosophila melanogaster. Genetic studies in D. melanogaster have shown that the mei-W68 gene is required for all meiotic gene conversion and crossing-over. We cloned mei-W68 using a new genetic...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Chromosome Mapping
- Cloning, Molecular
- Crosses, Genetic
- Crossing Over, Genetic
- DNA Primers
- DNA Topoisomerases, Type I
- DNA, Complementary
- Drosophila melanogaster
- Female
- Genes, Insect
- Insect Proteins
- Male
- Meiosis
- Molecular Sequence Data
- Mutation