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Article

mei-W68 in Drosophila melanogaster encodes a Spo11 homolog: evidence that the mechanism for initiating meiotic recombination is conserved.

Genes & development - 15 Sept 1998

McKim K S, Hayashi-Hagihara A

Abstract excerpt

Meiotic recombination requires the action of several gene products in both Saccharomyces cerevisiae and Drosophila melanogaster. Genetic studies in D. melanogaster have shown that the mei-W68 gene is required for all meiotic gene conversion and crossing-over. We cloned mei-W68 using a new genetic mapping method in which P elements are used to promote crossing-over at their insertion sites. This resulted in the...

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Identifiers

PMID: 9744869
DOI: 10.1101/gad.12.18.2932
PMCID: PMC317166

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