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Article

Drosophila mus301/spindle-C encodes a helicase with an essential role in double-strand DNA break repair and meiotic progression.

Genetics - 1 Nov 2006

McCaffrey Ruth, St Johnston Daniel, González-Reyes Acaimo

Abstract excerpt

mus301 was identified independently in two genetic screens, one for mutants hypersensitive to chemical mutagens and another for maternal mutants with eggshell defects. mus301 is required for the proper specification of the oocyte and for progression through meiosis in the Drosophila ovary. We have cloned mus301 and show that it is a member of the Mus308 subfamily of ATP-dependent helicases and the closest homolog...

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Identifiers

PMID: 16888338
DOI: 10.1534/genetics.106.058289
PMCID: PMC1667076

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Source receipt: pubmed, retrieved 7 Sept 2026.

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