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Article

Lack of association of OPRM1 and ABCB1 single-nucleotide polymorphisms to oxycodone response in postoperative pain.

Journal of clinical pharmacology - 1 Feb 2012

Zwisler Stine T, Enggaard Thomas P, Mikkelsen Soeren, Verstuyft Céline, Becquemont Laurent, Sindrup Soeren H, Brosen Kim

Abstract excerpt

PURPOSE: The aim of the study was to search for an association between the single-nucleotide polymorphisms A118G in OPRM1 and C3435T and G2677T/A in ABCB1 and the analgesic effect of intravenous oxycodone in postoperative pain. METHODS: There were 268 patients with postoperative pain after, primarily, thyroidectomy. At given times during the first 24 hours postoperatively, their pain was rated at rest and during...

Read the complete abstract on PubMed

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Share to Aged, 80 and over
Share to Analgesics, Opioid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to ATP Binding Cassette Transporter, Subfamily B

Share to Double-Blind Method

Share to Pain, Postoperative

Share to Receptors, Opioid, mu

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Source

Identifiers

PMID: 21383334
DOI: 10.1177/0091270010397729

Genes

ABCB1
OPRM1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Lack of association of OPRM1 and ABCB1 single-nucleotide polymorphisms to oxycodone response in postoperative pain.PMID 21383334Read ↗

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Effect of common OPRM1, COMT, SLC6A4, ABCB1, and CYP2B6 polymorphisms on perioperative analgesic and propofol demands on patients subjected to thyroidectomy surgery.Semantic proximity Read ↗

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