Article
Isolation and functional characterization of the human 90K promoter.
Genomics - 15 Apr 1999
Brakebusch C, Sures I, Jallal B, Mossie K, Fusco O, Iacobelli S, Ullrich A
Abstract excerpt
90K is a secreted protein thought to be involved in the body's defense against pathogens and cancer. To elucidate its transcriptional regulation, the promoter of human 90K (HGMW-approved symbol LGAL S3BP) was isolated and characterized. Analysis of the 3. 3-kb 5'-flanking region revealed that it is a TATA-less promoter, but neither GC-rich nor dependent on SP1 sites. RNase protection assays detected one major...
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