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Article

Functional Characterization of the Human Factor VII 5′-Flanking Region

1 Jan 1996

Abstract excerpt

Factor VII is a vitamin K-dependent coagulation protein essential for proper hemostasis. The human Factor VII gene spans 13 kilobase pairs and is located on chromosome 13 just 2.8 kilobase pairs 5' to the Factor X gene. In this report, we show that Factor VII transcripts are restricted to the liver and that steady state levels of mRNA are much lower than those of Factor X. The major transcription start site is...

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PMID: 8576177
DOI: 10.1074/jbc.271.3.1738

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