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Article

Disseminated colorectal tumor cells in organs prone to metastasis detected by new double enriched nested-PCR in comparison with recognized assays.

Oncology reports - 1 May 2011

Kraus Magdalena C, Linnemann Ulrich, Berger Martin R

Abstract excerpt

Hypothetically, K-ras mutations can be used as a marker of disseminated tumor cells (DTCs) in patients with K-ras mutated primary carcinoma. This study focused on the development of a useful assay for detecting low numbers of DTCs in potential target tissues of metastatic K-ras codon 12 mutated c...

Topics

Aged
Aged, 80 and over
Biomarkers, Tumor
Cell Line, Tumor
Colorectal Neoplasms
Female
Genes, ras
Humans
Male
Middle Aged
Mutation
Neoplasm Metastasis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neoplasm Staging

Polymerase Chain Reaction

Source

Identifiers

PMID: 21369707
DOI: 10.3892/or.2011.1203

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-21369707-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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