Article
Prognostic value of disseminated colorectal tumor cells in the liver: results of follow-up examinations.
International journal of colorectal disease - 1 Jul 2004
Linnemann Ulrich, Schimanski Christoph C, Gebhardt Christoph, Berger Martin R
Abstract excerpt
BACKGROUND AND AIMS: Dissemination of tumor cells is an initial step in metastatic disease. Detection of disseminated tumor cells (DTC) in blood, bone marrow and lymph nodes has been associated with reduced disease-free survival, but to date there are no data for hepatic DTC. We investigated the prognostic relevance of hepatic DTC that are present in patients with colorectal cancer (CRC) at the time of surgery....
Topics
- Adult
- Aged
- Aged, 80 and over
- Biomarkers, Tumor
- Codon
- Colorectal Neoplasms
- Female
- Follow-Up Studies
- Genes, ras
- Humans
- Liver
- Liver Neoplasms
- Male
- Middle Aged
- Mutation
- Neoplastic Cells, Circulating
- Prognosis
- Prospective Studies
