Carcinoembryonic antigen-related cell adhesion molecule 16 interacts with alpha-tectorin and is mutated in autosomal dominant hearing loss (DFNA4).

doi:10.1073/pnas.1005842108

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Article

Carcinoembryonic antigen-related cell adhesion molecule 16 interacts with alpha-tectorin and is mutated in autosomal dominant hearing loss (DFNA4).

Proceedings of the National Academy of Sciences of the United States of America - 8 Mar 2011

Zheng Jing, Miller Katharine K, Yang Tao, Hildebrand Michael S, Shearer A Eliot, DeLuca Adam P, Scheetz Todd E, Drummond Jennifer, Scherer Steve E, Legan P Kevin, Goodyear Richard J, Richardson Guy P, Cheatham Mary Ann, Smith Richard J, Dallos Peter

Abstract excerpt

We report on a secreted protein found in mammalian cochlear outer hair cells (OHC) that is a member of the carcinoembryonic antigen-related cell adhesion molecule (CEACAM) family of adhesion proteins. Ceacam16 mRNA is expressed in OHC, and its protein product localizes to the tips of the tallest stereocilia and the tectorial membrane (TM). This specific localization suggests a role in maintaining the integrity of...

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PMID: 21368133
DOI: 10.1073/pnas.1005842108
PMCID: PMC3054008

Genes

CEACAM16

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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