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Article

Otogelin, otogelin-like, and stereocilin form links connecting outer hair cell stereocilia to each other and the tectorial membrane.

Proceedings of the National Academy of Sciences of the United States of America - 17 Dec 2019

Avan Paul, Le Gal Sébastien, Michel Vincent, Dupont Typhaine, Hardelin Jean-Pierre, Petit Christine, Verpy Elisabeth

Abstract excerpt

The function of outer hair cells (OHCs), the mechanical actuators of the cochlea, involves the anchoring of their tallest stereocilia in the tectorial membrane (TM), an acellular structure overlying the sensory epithelium. Otogelin and otogelin-like are TM proteins related to secreted epithelial mucins. Defects in either cause the DFNB18B and DFNB84B genetic forms of deafness, respectively, both characterized by...

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Identifiers

PMID: 31776257
DOI: 10.1073/pnas.1902781116
PMCID: PMC6926040

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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