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Article

Exome sequencing identifies a novel CEACAM16 mutation associated with autosomal dominant nonsyndromic hearing loss DFNA4B in a Chinese family.

Journal of human genetics - 1 Mar 2015

Wang Honghan, Wang Xinwei, He Chufeng, Li Haibo, Qing Jie, Grati Mhamed, Hu Zhengmao, Li Jiada, Hu Yiqiao, Xia Kun, Mei Lingyun, Wang Xingwei, Yu Jianjun, Chen Hongsheng, Jiang Lu, Liu Yalan, Men Meichao, Zhang Hailin, Guan Liping, Xiao Jingjing, Zhang Jianguo, Liu Xuezhong, Feng Yong

Abstract excerpt

Autosomal dominant nonsyndromic hearing loss (ADNSHL/DFNA) is a highly genetically heterogeneous disorder. Hitherto only about 30 ADNSHL-causing genes have been identified and many unknown genes remain to be discovered. In this research, genome-wide linkage analysis mapped the disease locus to a 4.3 Mb region on chromosome 19q13 in SY-026, a five-generation nonconsanguineous Chinese family affected by late-onset...

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Source

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Identifiers

PMID: 25589040
DOI: 10.1038/jhg.2014.114
PMCID: PMC4375019

Genes

CEACAM16

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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