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Article

The effect of pre-mutation of X chromosome CGG trinucleotide repeats on brain anatomy.

Brain : a journal of neurology - 1 Dec 2004

Moore Caroline J, Daly Eileen M, Tassone Flora, Tysoe Carolyn, Schmitz Nicole, Ng Virginia, Chitnis Xavier, McGuire Philip, Suckling John, Davies Kay E, Hagerman Randi J, Hagerman Paul J, Murphy Kieran C, Murphy Declan G M

Abstract excerpt

Expanded trinucleotide repeats are associated with several neuropsychiatric disorders, including fragile X syndrome (FraX) which is the most common inherited form of mental retardation. It is currently thought that FraX results from having >200 CGG trinucleotide repeats, with consequent methylation of the fragile X mental retardation gene (FMR1) and loss of FMR1 protein (FMRP). Pre-mutation carriers of FraX (with...

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Share to Chromosomes, Human, X

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Fragile X Mental Retardation Protein

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Share to Image Processing, Computer-Assisted

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Source

Identifiers

PMID: 15483045
DOI: 10.1093/brain/awh256

Genes

FMR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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