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Article

Psychological symptoms correlate with reduced hippocampal volume in fragile X premutation carriers.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Apr 2010

Adams P E, Adams J S, Nguyen D V, Hessl D, Brunberg J A, Tassone F, Zhang W, Koldewyn K, Rivera S M, Grigsby J, Zhang L, Decarli C, Hagerman P J, Hagerman R J

Abstract excerpt

Fragile X-associated tremor/ataxia syndrome (FXTAS) is a neurodegenerative disorder occurring in male and occasional female carriers of a premutation expansion (55-200 CGG repeats) of the fragile X mental retardation 1 gene (FMR1). This study assessed the relationship between hippocampal volume a...

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Identifiers

PMID: 19908235
DOI: 10.1002/ajmg.b.31046
PMCID: PMC2868927

Genes

FMR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19908235-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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