Article
Association between polymorphisms in the promoter region of interleukin-10 and susceptibility to inflammatory bowel disease.
Molecular biology reports - 1 Mar 2014
Lv Hongchao, Jiang Yongshuai, Li Jin, Zhang Mingming, Shang Zhenwei, Zheng Jiajia, Wu Xin, Liu Panpan, Zhang Ruijie, Yu Huimin
Abstract excerpt
The aim of this study was to assess the association of polymorphisms in the promoter region of the IL-10 gene with the risk of inflammatory bowel disease (IBD), including Crohn's disease (CD) and ulcerative colitis (UC). Fifteen studies (3,693 cases and 4,574 controls) were included in a meta-analysis of association between IL-10 -1082G/A, -819C/T and -592C/A polymorphisms, and IBD, CD and UC using allele...
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