Article
An exon 5-less splice variant of the extracellular calcium-sensing receptor rescues absence of the full-length receptor in the developing mouse lung.
Experimental lung research - 1 Jun 2011
Finney Brenda, Wilkinson William J, Searchfield Lydia, Cole Martin, Bailey Stacey, Kemp Paul J, Riccardi Daniela
Abstract excerpt
The authors have recently demonstrated that, in the developing mouse lung, fetal plasma Ca(2+) suppresses branching morphogenesis and cell proliferation while promoting fluid secretion via activation of the extracellular Ca(2+)-sensing receptor (CaSR). The aim of the current study was to further elucidate the role of Ca(2+) in lung development by studying the effects of extracellular Ca(2+) on fetal lung...
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