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Article

Mice with markedly reduced PACAP (PAC(1)) receptor expression by targeted deletion of the signal peptide.

Journal of neurochemistry - 1 Nov 2000

Hashimoto H, Shintani N, Nishino A, Okabe M, Ikawa M, Matsuyama S, Itoh K, Yamamoto K, Tomimoto S, Fujita T, Hagihara N, Mori W, Koyama Y, Matsuda T, Nagata S, Baba A

Abstract excerpt

In an attempt to study the pituitary adenylate cyclase-activating polypeptide (PACAP) type 1 (PAC(1)) receptor (PAC(1)R) function in vivo and to produce a mouse model with altered expression of PAC(1)R, we have used gene targeting in embryonic stem cells to disrupt exon 2 of the PAC(1)R gene, whi...

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Identifiers

PMID: 11032869
DOI: 10.1046/j.1471-4159.2000.0751810.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-11032869-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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Mice with markedly reduced PACAP (PAC(1)) receptor expression by targeted deletion of the signal peptide.PMID 11032869Read ↗

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