Article
Profiling of genetic variations in inflammation pathway genes in relation to bladder cancer predisposition.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Apr 2008
Yang Hushan, Gu Jian, Lin Xin, Grossman H Barton, Ye Yuanqing, Dinney Colin P, Wu Xifeng
Abstract excerpt
PURPOSE: Compelling evidence has indicated that inflammation plays an important role in cancer development. We sought to test the hypothesis that common sequence variants in the inflammation pathway modulate bladder cancer risk. EXPERIMENTAL DESIGN: We genotyped 59 potentially functional single nucleotide polymorphisms from 35 candidate inflammation genes in a case-control study including 635 Caucasian bladder...
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