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Article

Genetic variation in PPARGC1A may affect the role of diet-associated inflammation in colorectal carcinogenesis.

Oncotarget - 31 Jan 2017

Cho Young Ae, Lee Jeonghee, Oh Jae Hwan, Chang Hee Jin, Sohn Dae Kyung, Shin Aesun, Kim Jeongseon

Abstract excerpt

The role of inflammation in colorectal carcinogenesis may differ according to individuals' genetic variations. Therefore, we investigated whether genetic susceptibility alters the association between inflammatory potential of diet and the risk of colorectal cancer within the Korean population. We genotyped four polymorphisms in four genes (IL1B, TNF, PPARG, and PPARGC1A) and calculated the dietary inflammatory...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28051997
DOI: 10.18632/oncotarget.14347
PMCID: PMC5352421

Genes

PPARG
TNF

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