Article

Prevalence of mismatch repair genes mutations and clinical activity of PD-1 therapy in Chinese prostate cancer patients

2022-08-17

Abstract excerpt

Prostate cancer (PCa) patients with mismatch repair (MMR) genes mutations are potentially responsive to immune checkpoint blockade (ICB). However, aberrations in MMR genes were rare in PCa and there is evidence that MMR genes mutations are highly ethnic-specific. Thus, the prevalence and clinical characteristics of this subgroup in Chinese PCa patients are largely unknown. Furthermore, why some of these patients d...

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Literature Corpus work: 52ca6322-a22c-504c-af6d-dc5b6988cace
DOI: 10.21203/rs.3.rs-1957915/v1

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