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Article

Enzyme-based amperometric platform to determine the polymorphic response in drug metabolism by cytochromes P450.

Analytical chemistry - 15 Mar 2011

Panicco Paola, Dodhia Vikash R, Fantuzzi Andrea, Gilardi Gianfranco

Abstract excerpt

"Personalized medicine" is a new concept in health care, one aspect of which defines the specificity and dosage of drugs according to effectiveness and safety for each patient. Dosage strongly depends from the rate of metabolism which is primarily regulated by the activity of cytochrome P450. In addition to the need for a genetic characterization of the patients, there is also the necessity to determine the...

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PMID: 21348440
DOI: 10.1021/ac200119b

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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