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Article

Real-time and label-free detection of VKORC1 genes based on a magnetoelastic biosensor for warfarin therapy.

Journal of materials chemistry. B - 7 Aug 2020

Sang Shengbo, Guo Xing, Wang Jingzhe, Li Hongmei, Ma Xingyi

Abstract excerpt

Various thrombotic disorders have been treated with the anticoagulant warfarin. However, a small change in warfarin concentration may lead to drug adverse reactions or therapeutic failure due to its narrow therapeutic index. Therefore, the dose of warfarin must be monitored for each patient during therapy in real-time and in a sensitive and stable manner. In this work, we designed a magnetoelastic (ME) biosensor...

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PMID: 32426797
DOI: 10.1039/d0tb00354a

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