Article
Cerium dioxide-doped carboxyl fullerene as novel nanoprobe and catalyst in electrochemical biosensor for amperometric detection of the CYP2C19*2 allele in human serum.
Biosensors & bioelectronics - 15 Apr 2018
Zhang Chengli, He Junlin, Zhang Yuchan, Chen Jun, Zhao Yilin, Niu Yazhen, Yu Chao
Abstract excerpt
The disposition dose of clopidogrel is different in CYP2C19*2 gene carriers and non-carriers. High-dose clopidogrel has been recommended to overcome a low-responsiveness to clopidogrel in patients with the CYP2C19*2 gene. To guide the choice of clopidogrel dosage and catalyse a development in the field of personalized therapy, we developed an ultrasensitive electrochemical biosensor to detect CYP2C19*2 gene. We...
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