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Article

Association between Gly1619ARG polymorphism of IGF2R domain 11 (rs629849) and advanced stage of oral cancer.

Medical oncology (Northwood, London, England) - 1 Jun 2012

Yoon Angela J, Zavras Athanasios I, Chen Mu-Kuan, Lin Chiao-Wen, Yang Shun-Fa

Abstract excerpt

Insulin-like growth factor II receptor (IGF2R) degrades mitogen and hence is associated with tumor suppressor function. The aim of this study was to assess whether genetic variation in the mitogen-binding domain of IGF2R, Gly1619Arg, disrupts normal function of IGF2R and contributes to further progression and distant metastasis of localized oral squamous cell carcinoma (OSCC). Gly1619Arg polymorphism of IGF2R...

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Share to Carcinoma, Squamous Cell
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mouth Neoplasms

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Share to Polymorphism, Restriction Fragment Length

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Share to Receptor, IGF Type 2

Source

Identifiers

PMID: 21347719
DOI: 10.1007/s12032-011-9863-6

Genes

IGF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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