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Article

Relationship between insulin-like growth factor axis gene polymorphisms and clinical outcome in advanced gastric cancer patients treated with FOLFOX.

Oncotarget - 24 May 2016

Oh Sung Yong, Shin Aesun, Kim Seong-Geun, Hwang Jung-Ah, Hong Seung Hyun, Lee Yeon-Su, Kwon Hyuk-Chan

Abstract excerpt

The insulin-like growth factor (IGF) axis plays a crucial role in proliferation, differentiation, migration, angiogenesis, and apoptosis. The present study evaluated the associations between IGF axis single-nucleotide polymorphisms (SNPs) and clinical outcomes in advanced gastric cancer (AGC) patients treated with oxaliplatin, 5-fluorouracil, and leucovorin (FOLFOX). A total of 190 patients undergoing FOLFOX...

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Source

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Identifiers

PMID: 27144430
DOI: 10.18632/oncotarget.9100
PMCID: PMC5058750

Genes

IGF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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