Article
Association of hepatitis B virus subgenotypes and basal core promoter/precore region variants with the clinical features of patients with acute hepatitis.
Journal of gastroenterology - 1 Jan 2008
Hayashi Kazuhiko, Katano Yoshiaki, Takeda Yasushi, Honda Takashi, Ishigami Masatoshi, Itoh Akihiro, Hirooka Yoshiki, Nakano Isao, Yoshioka Kentaro, Toyoda Hidenori, Kumada Takashi, Goto Hidemi
Abstract excerpt
BACKGROUND: In endemic areas, including Japan, basal core promoter (BCP) and precore (PC) variants of hepatitis B virus (HBV) have been reported to be associated with the clinical outcome of acute hepatitis B patients. However, the associations of BCP/PC variants with clinical outcomes have not been observed in nonendemic areas. HBV subgenotypes, which show geographic variations in prevalence, may underlie this...
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