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Article

Alternative initial proton acceptors for the D pathway of Rhodobacter sphaeroides cytochrome c oxidase.

Biochemistry - 12 Apr 2011

Varanasi Lakshman, Hosler Jonathan

Abstract excerpt

To characterize protein structures that control proton uptake, we assayed forms of cytochrome c oxidase (CcO) containing a carboxyl or a thiol group in line with the initial, internal waters of the D pathway for proton transfer in the presence and absence of subunit III. Subunit III provides approximately half of the protein surrounding the entry region of the D pathway. The N139D/D132N mutant contains a carboxyl...

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Identifiers

PMID: 21344856
DOI: 10.1021/bi102002v
PMCID: PMC3082432

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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