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Article

Crystallographic and online spectral evidence for role of conformational change and conserved water in cytochrome oxidase proton pump.

Proceedings of the National Academy of Sciences of the United States of America - 25 Jan 2011

Liu Jian, Qin Ling, Ferguson-Miller Shelagh

Abstract excerpt

Crystal structures in both oxidized and reduced forms are reported for two bacterial cytochrome c oxidase mutants that define the D and K proton paths, showing conformational change in response to reduction and the loss of strategic waters that can account for inhibition of proton transfer. In th...

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Identifiers

PMID: 21205904
DOI: 10.1073/pnas.1012846108
PMCID: PMC3029696

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21205904-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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