Article
IL-10 inhibits inflammatory cytokines released by fetal mouse lung fibroblasts exposed to mechanical stretch.
Pediatric pulmonology - 1 Jul 2011
Hawwa Renda L, Hokenson Michael A, Wang Yulian, Huang Zheping, Sharma Surendra, Sanchez-Esteban Juan
Abstract excerpt
BACKGROUND: Mechanical ventilation plays an important role in the pathogenesis of bronchopulmonary dysplasia. However, the molecular mechanisms by which excessive stretch induces lung inflammation are not well characterized. OBJECTIVES: In this study, we investigated in vitro the contribution of lung mesenchymal cells to the inflammatory response mediated by mechanical stretch and the potential protective role of...
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